Epigenetics

GW6471 View larger

GW6471

AT8486

CAS 880635-03-0

More details

Molarity Calculation Cart®

HOW TO ORDER

$27.00

$27.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $12.15 Total: $1,215.00
150 $14.04 Total: $702.00
125 $16.47 Total: $411.75
110 $19.44 Total: $194.40
15 $22.95 Total: $114.75

Data sheet

Molecular FormulaC35H36F3N3O4
Molecular Weight619.67
CAS Numbers880635-03-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCCC(=O)NC[C@H](Cc1ccc(OCCc2nc(oc2C)-c2ccccc2)cc1)NC(C)=CC(=O)c1ccc(cc1)C(F)(F)F
ReferencesAbu Aboud O, et al. Inhibition of PPAR? induces cell cycle arrest and apoptosis, and synergizes with glycolysis inhibition in kidney cancer cells. PLoS One. 2013 Aug 7;8[8] e71115.

More info

GW6471 is an antagonist of PPAR? with IC50 of 0.24 ? M. GW6471 enhances the binding affinity of the PPAR ? ligand-binding domain to the co-repressor proteins SMRT and NCoR.