Epigenetics

OTS186935 FA View larger

OTS186935 FA

AT12344L1

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HOW TO ORDER

$83.00

$83.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $37.35 Total: $3,735.00
150 $43.16 Total: $2,158.00
125 $50.63 Total: $1,265.75
110 $59.76 Total: $597.60
15 $70.55 Total: $352.75

Data sheet

Molecular FormulaC26H28ClN5O4
Molecular Weight509.98
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOC1=C(C2=CN(C=CC(N3C[C@H](CC3)NCC4=CC=NC=C4)=C5)C5=N2)C=C(C(OC)=C1)Cl.[H]C(O)=O
ReferencesVougiouklakis T, et al. Development of novel SUV39H2 inhibitors that exhibit growth suppressive effects in mouse xenograft models and regulate the phosphorylation of H2AX. Oncotarget. 2018 Aug 7;9[61] 31820-31831.

More info

OTS186935 FA is a protein methyltransferase SUV39H2 inhibitor.OTS186935 FA inhibits tumor growth in MDA-MB-231 breast cancer cells and A549 lung cancer cells.