Epigenetics

Resminostat hydrochloride View larger

Resminostat hydrochloride

AT4370

CAS 1187075-34-8

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$34.00

$34.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $15.30 Total: $1,530.00
150 $17.68 Total: $884.00
125 $20.74 Total: $518.50
110 $24.48 Total: $244.80
15 $28.90 Total: $144.50

Data sheet

Molecular FormulaC16H20ClN3O4S
Molecular Weight385.86
CAS Numbers1187075-34-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.CN(C)Cc1ccc(cc1)S(=O)(=O)n1ccc(C=CC(=O)NO)c1
ReferencesMandl-Weber S, et al. The novel inhibitor of histone deacetylase resminostat [RAS2410] inhibits proliferation and induces apoptosis in multiple myeloma [MM] cells. Br J Haematol. 2010 May;149[4] 518-28.

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Resminostat hydrochloride (RAS2410 hydrochloride) is an effective inhibitor of HDAC1HDAC3HDAC6 (IC50: 42.550.171.8 nM), respectively, and shows less potent activities against HDAC8 (IC50: 877 nM).