Epigenetics

SC-236 View larger

SC-236

AT8505

CAS 170569-86-5

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$26.00

$26.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $11.70 Total: $1,170.00
150 $13.52 Total: $676.00
125 $15.86 Total: $396.50
110 $18.72 Total: $187.20
15 $22.10 Total: $110.50

Data sheet

Molecular FormulaC16H11ClF3N3O2S
Molecular Weight401.79
CAS Numbers170569-86-5
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeNS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(Cl)cc1)C(F)(F)F
ReferencesKim S J , Jeong H J , Moon P D , et al. The COX-2 inhibitor SC-236 exerts anti-inflammatory effects by suppressing phosphorylation of ERK in a murine model[J]. Life Sciences, 2007, 81[11] 0-872.

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SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 ?M and 17.8 ?M for COX-2 and COX-1, respectively).