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View larger BRMBRG1 ATP Inhibitor-1
AT10616
CAS 2270879-17-7
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $300.90 | Total: $1,504.50 |
| 1 | 10 | $254.88 | Total: $2,548.80 |
| 1 | 25 | $215.94 | Total: $5,398.50 |
| 1 | 50 | $184.08 | Total: $9,204.00 |
| 1 | 100 | $159.30 | Total: $15,930.00 |
Data sheet
| Molecular Formula | C11H9F3N4O2S |
| Molecular Weight | 318.27 |
| CAS Numbers | 2270879-17-7 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | OCc1cnc(F)cc1NC(=O)Nc1cc(ns1)C(F)F |
| References | Papillon JPN, et al. Discovery of Orally Active Inhibitors of Brahma Homolog [BRM]SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 [BRG1]SMARCA4-Mutant Cancers. J Med Chem. 2018 Nov 21;61[22] 10155-10172 |
More info
BRMBRG1 ATP Inhibitor-1 is an allosteric dual Brahma homolog (BRM)SWISNF related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) and BRG1SMARCA4 ATPase activity inhibitor (IC50s<0.005 ?M).