Epigenetics

T-3775440 hydrochloride View larger

T-3775440 hydrochloride

AT13055

CAS 1422535-52-1

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$82.00

$82.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $36.90 Total: $3,690.00
150 $42.64 Total: $2,132.00
125 $50.02 Total: $1,250.50
110 $59.04 Total: $590.40
15 $69.70 Total: $348.50

Data sheet

Molecular FormulaC18H23ClN4O
Molecular Weight346.85
CAS Numbers1422535-52-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.Cn1cc(cn1)C(=O)Nc1ccc(cc1)[C@@H]1C[C@H]1NCC1CC1
ReferencesIshikawa Y, et al. A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells. Mol Cancer Ther. 2017 Feb;16[2] 273-284.

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T-3775440 hydrochloride is an irreversible inhibitor of lysine-specific histone demethylase (LSD1)(IC50 : 2.1 nM).