Epigenetics

ZEN-3219 View larger

ZEN-3219

AT13392

CAS 1952264-34-4

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$67.00

$67.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $30.15 Total: $3,015.00
150 $34.84 Total: $1,742.00
125 $40.87 Total: $1,021.75
110 $48.24 Total: $482.40
15 $56.95 Total: $284.75

Data sheet

Molecular FormulaC19H18N2O3
Molecular Weight322.36
CAS Numbers1952264-34-4
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC=1C(C2=CN(CC3=CC=C(C=C3)C4CO4)C(=O)C=C2)=C(C)ON1
ReferencesKharenko OA, et al. Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain [BET] Inhibitors Targeting a Methionine. J Med Chem. 2018;61[18] 8202-8211.

More info

ZEN-3219 is a BET inhibitor, which has inhibitory effect on BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2). ZEN-3219 has inhibitory effect on BRD4(BD1), The IC50 values of BRD4(BD2) and BRD4(BD1BD2) were 0.48, 0.16 and 0.47 ?M, respectively. ZEN-3219 is a component of PROTAC molecule and can induce BRD4 degradation.