Epigenetics

UNC6852 View larger

UNC6852

AT13954

CAS 2688842-08-0

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$115.00

$115.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $51.75 Total: $5,175.00
150 $59.80 Total: $2,990.00
125 $70.15 Total: $1,753.75
110 $82.80 Total: $828.00
15 $97.75 Total: $488.75

Data sheet

Molecular FormulaC43H48N10O6S
Molecular Weight832.97
CAS Numbers2688842-08-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCNC(=O)c2ccc(cc2)-c2cnc(NCc3ccco3)n3cnnc23)C(C)(C)C)cc1
ReferencesPotjewyd F, et al. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader. Cell Chem Biol. 2020 Jan 16;27[1] 47-56.e15.

More info

UNC6852 contains an EED ligand (IC50 = 247 nM) and a von Hippel-Lindau ligand and is a selective polycomb repressive complex 2 (PRC2) degrader based on PROTAC.