Epigenetics

SS-208 View larger

SS-208

AT16936

CAS 2245942-72-5

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$76.00

$76.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $34.20 Total: $3,420.00
150 $39.52 Total: $1,976.00
125 $46.36 Total: $1,159.00
110 $54.72 Total: $547.20
15 $64.60 Total: $323.00

Data sheet

Molecular FormulaC13H11Cl2N3O4
Molecular Weight344.15
CAS Numbers2245942-72-5
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeONC(=O)c1cc(CCNC(=O)c2ccc(Cl)c(Cl)c2)on1
ReferencesShen S, et al. Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models. J Med Chem. 2019 Sep 4.

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SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.