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View larger LSD1-IN-20
AT63140
CAS 1239589-91-3
1000 Items
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $286.45 | Total: $1,432.25 |
| 1 | 10 | $242.64 | Total: $2,426.40 |
| 1 | 25 | $205.57 | Total: $5,139.25 |
| 1 | 50 | $175.24 | Total: $8,762.00 |
| 1 | 100 | $151.65 | Total: $15,165.00 |
Data sheet
| Molecular Formula | C27H38N6O2 |
| Molecular Weight | 478.63 |
| CAS Numbers | 1239589-91-3 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(C=1C2=C(N=C(NCCCN(C)C)N1)C=C(OC)C(OC)=C2)C3CCN(CC4=CC=CC=C4)CC3 |
| References | Menna M, et al. Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models. Eur J Med Chem. 2022 Jul 5;237 114410. |
More info
Lsd1-in-20 is a potent dual inhibitor of LSD1G9a with Ki values of 0.44 and 0.68 ?M, respectively. LSD1-IN-20 showed antiproliferative activity against THP-1 leukemia cells and MDA-MB-231 breast cancer cells in vitro, with IC50 of 0.51 and 1.60 ?M, respectively, at 72 h.