Epigenetics

TNG908 View larger

TNG908

AT73494

CAS 2760481-53-4

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$283.00

$283.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $127.35 Total: $12,735.00
150 $147.16 Total: $7,358.00
125 $172.63 Total: $4,315.75
110 $203.76 Total: $2,037.60
15 $240.55 Total: $1,202.75

Data sheet

Molecular FormulaC21H23N5O2S
Molecular Weight409.51
CAS Numbers2760481-53-4
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(C(NC=1C=C(C)C(N)=NC1)=O)(=O)N2[C@H](CC[C@H](C)C2)C=3C=C4C(=CC3)SC=N4
ReferencesK. Briggs, et al. TNG908 is a brain-penetrant, MTA-cooperative PRMT5 inhibitor for the treatment of MTAP-deleted cancer.MOLECULAR TARGETED AGENTS 2

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TNG908 is an orally active and selective MTAP-co-PRMT5 inhibitor that crosses the blood-brain barrier and kills MTAP-deficient cancers.