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View larger MAK-683 hydrochloride
AT9681
CAS 2170606-94-5
Molarity Calculation Cart®
HOW TO ORDER
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $74.70 | Total: $7,470.00 |
| 1 | 50 | $86.32 | Total: $4,316.00 |
| 1 | 25 | $101.26 | Total: $2,531.50 |
| 1 | 10 | $119.52 | Total: $1,195.20 |
| 1 | 5 | $141.10 | Total: $705.50 |
Data sheet
| Molecular Formula | C20H18ClFN6O |
| Molecular Weight | 412.85 |
| CAS Numbers | 2170606-94-5 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | FC1=CC=C2C(CCO2)=C1CNC3=NC=C(C(C=CC=N4)=C4C)C5=NN=CN35.Cl |
| References | Dading Huang, et al. Binding Modes of Small-Molecule Inhibitors to the EED Pocket of PRC2. Chemphyschem. 2020 Feb 4;21[3] 263-271. |
More info
MAK683 hydrochloride is an inhibitor of embryonic ectoderm development (EED). MAK683 exhibits IC50s of 59, 26, 89 nM in EED Alphascreen binding, ELISA and LC-MS assay.