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View larger Tropifexor
AT4379
CAS 1383816-29-2
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $64.60 | Total: $323.00 |
| 1 | 10 | $54.72 | Total: $547.20 |
| 1 | 25 | $46.36 | Total: $1,159.00 |
| 1 | 50 | $39.52 | Total: $1,976.00 |
| 1 | 100 | $34.20 | Total: $3,420.00 |
Data sheet
| Molecular Formula | C29H25F4N3O5S |
| Molecular Weight | 603.58 |
| CAS Numbers | 1383816-29-2 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | OC(=O)c1cc(F)c2nc(sc2c1)N1[C@H]2CC[C@@H]1C[C@@H](C2)OCc1c(onc1-c1ccccc1OC(F)(F)F)C1CC1 |
| References | Tully DC,etal.Discovery of Tropifexor [LJN452], a Highly Potent Non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis [NASH].J Med Chem. 2017 Dec 28;60[24] 9960-9973. |
More info
Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM.