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> Function Modulators>Vadimezan (DMXAA)

Function Modulators

Vadimezan View larger

Vadimezan (DMXAA)

AOB5328

CAS: 117570-53-3

 

Chemical Name: DMXAA; ASA404; 5,6-Dimethylxanthenone 4-acetic acid

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Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $17.85 Total: $89.25
110 $15.12 Total: $151.20
125 $12.81 Total: $320.25
150 $10.92 Total: $546.00
1100 $9.45 Total: $945.00

Data sheet

Molecular FormulaC17H14O4
Molecular Weight282.29
CAS Numbers117570-53-3
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymASA404; ASA 404; ASA404; AS1404; AS 1404; AS1404; DMXAA; Vadimezan
IUPAC/Chemical Name(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)-acetic acid
InChl KeyXGOYIMQSIKSOBS-UHFFFAOYSA-N
InChl CodeInChI=1S/C17H14O4/c1-9-6-7-13-15(20)12-5-3-4-11(8-14(18)19)17(12)21-16(13)10(9)2/h3-7H,8H2,1-2H3,(H,18,19)
SMILES CodeO=C(O)CC1=CC=CC(C2=O)=C1OC3=C2C=CC(C)=C3C
References1) Lou YC, Kao YF, Chin KH, Chen JK, Tu JL, Chen C, Chou SH. Backbone resonance assignments of the 54 kDa dimeric C-terminal domain of murine STING in complex with DMXAA. Biomol NMR Assign. 2014 Dec 9. [Epub ahead of print] PubMed PMID: 25487675.

2) Gao P, Zillinger T, Wang W, Ascano M, Dai P, Hartmann G, Tuschl T, Deng L, Barchet W, Patel DJ. Binding-pocket and lid-region substitutions render human STING sensitive to the species-specific drug DMXAA. Cell Rep. 2014 Sep 25;8(6):1668-76. doi: 10.1016/j.celrep.2014.08.010. Epub 2014 Sep 4. PubMed PMID: 25199835.

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