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Vadimezan (DMXAA)
AOB5328
CAS: 117570-53-3
Chemical Name: DMXAA; ASA404; 5,6-Dimethylxanthenone 4-acetic acid
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $9.45 | Total: $945.00 |
| 1 | 50 | $10.92 | Total: $546.00 |
| 1 | 25 | $12.81 | Total: $320.25 |
| 1 | 10 | $15.12 | Total: $151.20 |
| 1 | 5 | $17.85 | Total: $89.25 |
Data sheet
| Molecular Formula | C17H14O4 |
| Molecular Weight | 282.29 |
| CAS Numbers | 117570-53-3 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | ASA404; ASA 404; ASA404; AS1404; AS 1404; AS1404; DMXAA; Vadimezan |
| IUPAC/Chemical Name | (5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)-acetic acid |
| InChl Key | XGOYIMQSIKSOBS-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C17H14O4/c1-9-6-7-13-15(20)12-5-3-4-11(8-14(18)19)17(12)21-16(13)10(9)2/h3-7H,8H2,1-2H3,(H,18,19) |
| SMILES Code | O=C(O)CC1=CC=CC(C2=O)=C1OC3=C2C=CC(C)=C3C |
| References | 1) Lou YC, Kao YF, Chin KH, Chen JK, Tu JL, Chen C, Chou SH. Backbone resonance assignments of the 54 kDa dimeric C-terminal domain of murine STING in complex with DMXAA. Biomol NMR Assign. 2014 Dec 9. [Epub ahead of print] PubMed PMID: 25487675. 2) Gao P, Zillinger T, Wang W, Ascano M, Dai P, Hartmann G, Tuschl T, Deng L, Barchet W, Patel DJ. Binding-pocket and lid-region substitutions render human STING sensitive to the species-specific drug DMXAA. Cell Rep. 2014 Sep 25;8(6):1668-76. doi: 10.1016/j.celrep.2014.08.010. Epub 2014 Sep 4. PubMed PMID: 25199835. |
More info
Mouse STING agonist; Potent tumor blood vessel-disrupting agent and cytokine inducer