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P7C3-A20
AOB87796
CAS: 1235481-90-9
Chemical Name: [3-(3,6-Dibromo-carbazol-9-yl)-2-fluoro-propyl]-(3-methoxy-phenyl)-amine
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $6.75 | Total: $675.00 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 5 | $12.75 | Total: $63.75 |
Data sheet
| Molecular Formula | C22H19Br2FN2O |
| Molecular Weight | 506.21 |
| CAS Numbers | 1235481-90-9 (free base) |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | P7C3-A20; P7C3A20; P7C3 A20 |
| IUPAC/Chemical Name | N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-3-methoxyaniline |
| InChl Key | XNLTWMQBJFWQOU-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C22H19Br2FN2O/c1-28-18-4-2-3-17(11-18)26-12-16(25)13-27-21-7-5-14(23)9-19(21)20-10-15(24)6-8-22(20)27/h2-11,16,26H,12-13H2,1H3 |
| SMILES Code | COC1=CC(NCC(F)CN2C3=C(C4=C2C=CC(Br)=C4)C=C(Br)C=C3)=CC=C1 |
| References | 1) Walker AK, Rivera PD, Wang Q, Chuang JC, Tran S, Osborne-Lawrence S, Estill SJ, Starwalt R, Huntington P, Morlock L, Naidoo J, Williams NS, Ready JM, Eisch AJ, Pieper AA, Zigman JM. The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis. Mol Psychiatry. 2014 Apr 22. 2) Pieper AA, McKnight SL, Ready JM. P7C3 and an unbiased approach to drug discovery for neurodegenerative diseases. Chem Soc Rev. 2014 Feb 11. [Epub ahead of print] PubMed PMID: 24514864. |
More info
More highly active analogue of neuroprotective agent P7C3 (AOB33371), displaying increased activity and an improved toxicity profile compared to P7C3 and demonstrating greater proneurogenic efficacy than a wide spectrum of currently marketed antidepressant drugs