Function Modulators

YK-11 View larger

YK-11

AOB36350

CAS: 1370003-76-1; 431579-34-9

 

Chemical Name: YK11; (17alpha,20E)-17,20-[(1-methoxyethylidene)bis-(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester

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Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $3.15 Total: $315.00
150 $3.64 Total: $182.00
125 $4.27 Total: $106.75
110 $5.04 Total: $50.40
15 $5.95 Total: $29.75

Data sheet

Molecular FormulaC25H34O6
Molecular Weight430.5
CAS Numbers1370003-76-1
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymYK-11; YK 11; YK11
IUPAC/Chemical Name(20E)-17α,20-[(1-methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid, methyl ester
InChl KeyKCQHQCDHFVGNMK-PQUNLUOYSA-N
InChl CodeInChI=1S/C25H34O6/c1-23-11-9-18-17-8-6-16(26)13-15(17)5-7-19(18)20(23)10-12-25(23)21(14-22(27)28-3)30-24(2,29-4)31-25/h13-14,17-20H,5-12H2,1-4H3/b21-14+/t17-,18+,19+,20-,23-,24?,25+/m0/s1
SMILES CodeO=C(OC)/C=C1OC(OC)(C)O[C@@]2/1CC[C@@]3([H])[C@]4([H])CCC5=CC(CC[C@]5([H])[C@@]4([H])CC[C@@]32C)=O
References1) 1. Kanno, Y., Hikosaka, R., Zhang, S.-Y., et al. (17α,20E)-17,20-[(1-Methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester (YK11) is a partial agonist of the androgen receptor. Biol. Pharm. Bull. 34(3), 318-323 (2011).

2) Kanno, Y., Ota, R., Someya, K., et al. Selective androgen receptor modulator, YK11, regulates myogenic differentiation of C2C12 myoblasts by follistatin expression. Biol. Pharm. Bull. 36(9), 1460-1465 (2013).

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Selective androgen receptor modulator (SARM), acting as a partial agonist, regulating myogenic differentiation of C2C12 myoblasts by follistatin expression