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View larger VU0092273
AOB1586
CAS 393110-43-5
Chemical Name: (4-Hydroxypiperidin-1-yl)(4-phenylethynyl)phenyl)methanone; VU0092273; VU0092273-7
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $75.65 | Total: $378.25 |
| 1 | 10 | $64.08 | Total: $640.80 |
| 1 | 25 | $54.29 | Total: $1,357.25 |
| 1 | 50 | $46.28 | Total: $2,314.00 |
| 1 | 100 | $40.05 | Total: $4,005.00 |
Data sheet
| Molecular Formula | C20H19NO2 |
| Molecular Weight | 305.38 |
| CAS Numbers | 393110-43-5 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | VU0092273, VU 0092273, VU-0092273 |
| IUPAC/Chemical Name | (4-hydroxypiperidin-1-yl)-[4-(2-phenylethynyl)phenyl]methanone |
| InChl Key | FPDBSDNGFNDSSK-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C20H19NO2/c22-19-12-14-21(15-13-19)20(23)18-10-8-17(9-11-18)7-6-16-4-2-1-3-5-16/h1-5,8-11,19,22H,12-15H2 |
| SMILES Code | O=C(N1CCC(O)CC1)C2=CC=C(C#CC3=CC=CC=C3)C=C2 |
| References | 1) Sheffler DJ, Wenthur CJ, Bruner JA, Carrington SJ, Vinson PN, Gogi KK, Blobaum AL, Morrison RD, Vamos M, Cosford ND, Stauffer SR, Daniels JS, Niswender CM, Conn PJ, Lindsley CW. Development of a novel, CNS-penetrant, metabotropic glutamate receptor 3 (mGlu3) NAM probe (ML289) derived from a closely related mGlu5 PAM. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3921-5. doi: 10.1016/j.bmcl.2012.04.112. Epub 2012 Apr 30. PubMed PMID: 22607673; PubMed Central PMCID: PMC3365510. |
More info
Novel positive allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5 PAM)