G Protein-Coupled Receptor Ligands

CHDI-180 View larger

CHDI-180

AOB11019

CAS: 1883792-80-0

 

Chemical Name: 6-(5-((5-Methoxypyridin-2-yl)methoxy)benzo[d]oxazol-2-yl)-2-methylpyridazin-3(2H)-one

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$59.00

$59.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $26.55 Total: $2,655.00
150 $30.68 Total: $1,534.00
125 $35.99 Total: $899.75
110 $42.48 Total: $424.80
15 $50.15 Total: $250.75

Data sheet

Molecular FormulaC19H16N4O4
Molecular Weight364.36
CAS Numbers1883792-80-0
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymCHDI-180R; CHDI 180R; CHDI180R;
IUPAC/Chemical Name6-(5-((5-Methoxypyridin-2-yl)methoxy)benzo[d]oxazol-2-yl)-2-methylpyridazin-3(2H)-one
InChl KeyGKFOHSAOICRNJW-UHFFFAOYSA-N
InChl CodeInChI=1S/C19H16N4O4/c1-23-18(24)8-6-15(22-23)19-21-16-9-13(5-7-17(16)27-19)26-11-12-3-4-14(25-2)10-20-12/h3-10H,11H2,1-2H3
SMILES CodeO=C1C=CC(C2=NC3=CC(OCC4=NC=C(C=C4)OC)=CC=C3O2)=NN1C
References1) Longbin Liu et al., Imaging Mutant Huntingtin Aggregates: Development of a Potential PET Ligand, J. Med. Chem. 2020, 63, 15, 8608–8633

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Novel potent ligand for mHTT protein, a huntingtin protein with an expanded polyglutamine stretch