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G Protein-Coupled Receptor Ligands

VU0183254 View larger

VU0183254

AOB1253

CAS: 663212-40-6

 

Chemical Name: 2-(4-Ethyl-5-furan-2-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-1-phenothiazin-10-yl-ethanone

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$31.00

$31.00 per 10 mg

Quantity Discount Table - Order More To Get More Price Discount

Quantity10 mgUnit Price ($/mg or $/Unit)Final Price
15 $26.35 Total: $131.75
110 $22.32 Total: $223.20
125 $18.91 Total: $472.75
150 $16.12 Total: $806.00
1100 $13.95 Total: $1,395.00

Data sheet

Molecular FormulaC22H18N4O2S2
Molecular Weight434.53
CAS Numbers663212-40-6
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymVU0183254; VU-0183254; VU 0183254
IUPAC/Chemical Name2-(4-Ethyl-5-furan-2-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-1-phenothiazin-10-yl-ethanone
InChl KeyASZRHXKUEMHBKN-UHFFFAOYSA-N
InChl CodeInChI=1S/C22H18N4O2S2/c1-2-25-21(17-10-7-13-28-17)23-24-22(25)29-14-20(27)26-15-8-3-5-11-18(15)30-19-12-6-4-9-16(19)26/h3-13H,2,14H2,1H3
SMILES CodeCCN1C(SCC(N2C3=C(C=CC=C3)SC4=CC=CC=C24)=O)=NN=C1C5=CC=CO5
References1) Jones PL, Pask GM, Romaine IM, Taylor RW, Reid PR, Waterson AG, Sulikowski GA, Zwiebel LJ. Allosteric antagonism of insect odorant receptor ion channels. PLoS One. 2012;7(1):e30304. doi: 10.1371/journal.pone.0030304. Epub 2012 Jan 17. PubMed PMID: 22272331; PubMed Central PMCID: PMC3260273.

2) Chen S, Luetje CW. Identification of new agonists and antagonists of the insect odorant receptor co-receptor subunit. PLoS One. 2012;7(5):e36784. doi: 10.1371/journal.pone.0036784. Epub 2012 May 8. PubMed PMID: 22590607; PubMed Central PMCID: PMC3348135.

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Novel antagonist of insect olfactory receptors (ORs) acting at a binding site on the Orco subunit