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View larger ML221 Bulk
AOB1262B
CAS No: 877636-42-5
Chemical Name: [4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl]-4-nitrobenzoate; CID-7217941
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity (mg or Unit) | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|
| 5 | $29.75 | Total: $148.75 |
| 10 | $25.20 | Total: $252.00 |
| 25 | $21.35 | Total: $533.75 |
| 50 | $18.20 | Total: $910.00 |
| 100 | $15.75 | Total: $1,575.00 |
Data sheet
| Molecular Formula | C17H11N3O6S |
| Molecular Weight | 385.35 |
| CAS Numbers | 877636-42-5 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | ML221; ML 221; ML-221. |
| IUPAC/Chemical Name | [4-oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 4-nitrobenzoate |
| InChl Key | UASIRTUMPRQVFY-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C17H11N3O6S/c21-14-8-13(10-27-17-18-6-1-7-19-17)25-9-15(14)26-16(22)11-2-4-12(5-3-11)20(23)24/h1-9H,10H2 |
| SMILES Code | O=C(OC1=COC(CSC2=NC=CC=N2)=CC1=O)C3=CC=C([N+]([O-])=O)C=C3 |
| References | 1) Roche J, Ramé C, Reverchon M, Mellouk N, Rak A, Froment P, Dupont J. Apelin (APLN) regulates progesterone secretion and oocyte maturation in bovine ovarian cells. Reproduction. 2017 Mar 1. pii: REP-16-0677. doi: 10.1530/REP-16-0677. [Epub ahead of print] PubMed PMID: 28250234. 2) Hall C, Ehrlich L, Venter J, O'Brien A, White T, Zhou T, Dang T, Meng F, Invernizzi P, Bernuzzi F, Alpini G, Lairmore TC, Glaser S. Inhibition of the apelin/apelin receptor axis decreases cholangiocarcinoma growth. Cancer Lett. 2017 Feb 1;386:179-188. doi: 10.1016/j.canlet.2016.11.025. PubMed PMID: 27894959. |
More info
Functional antagonist of the apelin (APJ) receptor