> G Protein-Coupled Receptor Ligands>[Ala11,D-Leu15]-Orexin B acetate

G Protein-Coupled Receptor Ligands

[Ala11,D-Leu15]-Orexin B acetate View larger

[Ala11,D-Leu15]-Orexin B acetate

ATP1975L

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$445.00

$445.00 per mg

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Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $200.25 Total: $20,025.00
150 $231.40 Total: $11,570.00
125 $271.45 Total: $6,786.25
110 $320.40 Total: $3,204.00
15 $378.25 Total: $1,891.25

Data sheet

Molecular FormulaC122H210N44O37S
Molecular Weight2917.31
CAS Numbers3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(O)=O.CSCC[C@@H](C(N)=O)NC([C@H]([C@H](O)C)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)NC(CNC([C@H](C)NC([C@H](C)NC([C@H](CC1=CNC=N1)NC([C@H](CC(N)=O)NC(CNC([C@H](CO)NC([C@H](C)NC([C@H](CCC(N)=O)NC([C@@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC(CNC([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC(CNC([C@H]2N(C([C@H]3N(C(CNC([C@H](CO)NC([C@H](CCCNC(N)=N)N)=O)=O)=O)CCC3)=O)CCC2)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
ReferencesAsahi S, et al. Development of an orexin-2 receptor selective agonist, [Ala[11], D-Leu[15]]orexin-B. Bioorg Med Chem Lett. 2003;13[1] 111-113.

More info

[Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM).