G Protein-Coupled Receptor Ligands

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ARB-272572 hydrochloride

AT83976

CAS 2377524-19-9

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$166.00

$166.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $74.70 Total: $7,470.00
150 $86.32 Total: $4,316.00
125 $101.26 Total: $2,531.50
110 $119.52 Total: $1,195.20
15 $141.10 Total: $705.50

Data sheet

Molecular FormulaC32H36N6O4.xClH
CAS Numbers2377524-19-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
ReferencesOffringa R,et al. The expanding role for small molecules in immuno-oncology. Nat Rev Drug Discov. 2022 Nov;21[11] 821-840.

More info

ARB-272572 hydrochloride is a small molecule PD-L1 inhibitor with an IC50 value of 400 pM for PD-1PD-L1 HTRF.ARB-272572 hydrochloride inhibits PD-1PD-L1 cell signaling by inducing homologous interactions with PD-L1 proteins.