G Protein-Coupled Receptor Ligands

5Z-7-Oxozeaenol View larger

5Z-7-Oxozeaenol

AT14055

CAS 253863-19-3

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$183.00

$183.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $82.35 Total: $8,235.00
150 $95.16 Total: $4,758.00
125 $111.63 Total: $2,790.75
110 $131.76 Total: $1,317.60
15 $155.55 Total: $777.75

Data sheet

Molecular FormulaC19H22O7
Molecular Weight362.37
CAS Numbers253863-19-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOc1cc(O)c2c(c1)C=CC[C@H](O)[C@H](O)C(=O)C=CC[C@H](C)OC2=O
ReferencesDakas PY, et al. Modular synthesis of radicicol A and related resorcylic acid lactones, potent kinase inhibitors. Angew Chem Int Ed Engl. 2007;46[36] 6899-902.

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5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-?-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is also an inhibitor of VEGF-R2 with IC50 of 52 nM.