G Protein-Coupled Receptor Ligands

Venadaparib View larger

Venadaparib

AT9430

CAS 1681017-83-3

More details

Molarity Calculation Cart®

HOW TO ORDER

$35.00

$35.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $15.75 Total: $1,575.00
150 $18.20 Total: $910.00
125 $21.35 Total: $533.75
110 $25.20 Total: $252.00
15 $29.75 Total: $148.75

Data sheet

Molecular FormulaC23H23FN4O2
Molecular Weight406.45
CAS Numbers1681017-83-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeFc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CC(CNC2CC2)C1
ReferencesCheng-Chang Chen, et al. A Small Molecule Restores Function to TRPML1 Mutant Isoforms Responsible for Mucolipidosis Type IV. Nat Commun. 2014 Aug 14;5 4681.

More info

Venadaparib (NOV140101) (IDX-1197) is a potent, selective and orally active PARP inhibitor with IC50s of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively. Venadaparib is insensitive to PARP-5. Venadaparib prevents the repair of DNA single-strand breaks (SSBs) and can be used in solid tumor research.