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View larger BMS202 hydrochloride (1675203-84-5(free base))
AT4696
CAS 2089334-95-0
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $34.00 | Total: $170.00 |
| 1 | 10 | $28.80 | Total: $288.00 |
| 1 | 25 | $24.40 | Total: $610.00 |
| 1 | 50 | $20.80 | Total: $1,040.00 |
| 1 | 100 | $18.00 | Total: $1,800.00 |
Data sheet
| Molecular Formula | C25H30ClN3O3 |
| Molecular Weight | 455.97 |
| CAS Numbers | 2089334-95-0 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.COc1nc(OCc2cccc(c2C)-c2ccccc2)ccc1CNCCNC(C)=O |
| References | Zak KM, Structural basis for small molecule targeting of the programmed death ligand 1 [PD-L1].Oncotarget. 2016 May 24;7[21] 30323-35. |
More info
BMS202 hydrochloride (1675203-84-5(free base)) (PD-1PD-L1 inhibitor 2 hydrochloride) is a small-molecule PD-1PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L1. Binding of BMS202 promotes PD-L1 dimerisation and blocks the PD-L1 PD1 interaction.