G Protein-Coupled Receptor Ligands

PD-1-IN-22 View larger

PD-1-IN-22

AT12379

CAS 2349372-98-9

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$99.00

$99.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $44.55 Total: $4,455.00
150 $51.48 Total: $2,574.00
125 $60.39 Total: $1,509.75
110 $71.28 Total: $712.80
15 $84.15 Total: $420.75

Data sheet

Molecular FormulaC25H25N5O4
Molecular Weight459.5
CAS Numbers2349372-98-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(NC1=C(C)C(=CC=C1)C=2C=C3C(=CC2)OCCO3)(=O)C=4C=5N(C=C(CNCCO)C4)C=NN5
ReferencesQin M, et al. Discovery of [1,2,4]Triazolo[4,3- a]pyridines as Potent Inhibitors Targeting the Programmed Cell Death-1Programmed Cell Death-Ligand 1 Interaction. J Med Chem. 2019 May 9;62[9] 4703-4715.

More info

PD-1-IN-22 is a potent inhibitor of the programmed cell death-1 (PD-1)programmed cell death-ligand 1 (PD-L1) interaction, with an IC50 of 92.3 nM.