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G Protein-Coupled Receptor Ligands
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View larger PD-1-IN-22
AT12379
CAS 2349372-98-9
1000 Items
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $84.15 | Total: $420.75 |
| 1 | 10 | $71.28 | Total: $712.80 |
| 1 | 25 | $60.39 | Total: $1,509.75 |
| 1 | 50 | $51.48 | Total: $2,574.00 |
| 1 | 100 | $44.55 | Total: $4,455.00 |
Data sheet
| Molecular Formula | C25H25N5O4 |
| Molecular Weight | 459.5 |
| CAS Numbers | 2349372-98-9 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(NC1=C(C)C(=CC=C1)C=2C=C3C(=CC2)OCCO3)(=O)C=4C=5N(C=C(CNCCO)C4)C=NN5 |
| References | Qin M, et al. Discovery of [1,2,4]Triazolo[4,3- a]pyridines as Potent Inhibitors Targeting the Programmed Cell Death-1Programmed Cell Death-Ligand 1 Interaction. J Med Chem. 2019 May 9;62[9] 4703-4715. |
More info
PD-1-IN-22 is a potent inhibitor of the programmed cell death-1 (PD-1)programmed cell death-ligand 1 (PD-L1) interaction, with an IC50 of 92.3 nM.