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View larger PF429242 dihydrochloride
AT12437
CAS 2248666-66-0
Molarity Calculation Cart®
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $13.95 | Total: $1,395.00 |
| 1 | 50 | $16.12 | Total: $806.00 |
| 1 | 25 | $18.91 | Total: $472.75 |
| 1 | 10 | $22.32 | Total: $223.20 |
| 1 | 5 | $26.35 | Total: $131.75 |
Data sheet
| Molecular Formula | C25H37Cl2N3O2 |
| Molecular Weight | 482.49 |
| CAS Numbers | 2248666-66-0 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.Cl.CCN(CC)Cc1ccc(cc1)C(=O)N(CCc1ccccc1OC)[C@@H]1CCNC1 |
| References | Hawkins JL, et al. Pharmacologic inhibition of site 1 protease activity inhibits sterol regulatory element-binding protein processing and reduces lipogenic enzyme gene expression and lipid synthesis in cultured cells and experimental animals. J Pharmacol Exp Ther. 2008 Sep;326[3] 801-8. |
More info
PF429242 dihydrochloride is a reversible and competitive inhibitor of S1P, with an IC50 of 175 nM.