G Protein-Coupled Receptor Ligands

TC-MCH 7c View larger

TC-MCH 7c

AT13101

CAS 864756-35-4

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$81.00

$81.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $36.45 Total: $3,645.00
150 $42.12 Total: $2,106.00
125 $49.41 Total: $1,235.25
110 $58.32 Total: $583.20
15 $68.85 Total: $344.25

Data sheet

Molecular FormulaC24H25FN2O3
Molecular Weight408.47
CAS Numbers864756-35-4
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeFc1ccc(COc2ccn(-c3ccc(OCCN4CCCC4)cc3)c(=O)c2)cc1
ReferencesIto M, et al. Melanin-concentrating hormone 1-receptor antagonist suppresses body weight gain correlated with high receptor occupancy levels in diet-induced obesity mice. Eur J Pharmacol. 2009 Dec 10;624[1-3] 77-83.

More info

TC-MCH 7c is an oral, selectable and blood-brain barrier penetrating MCH1R antagonist with IC50 performance of 5.6 nM against hMCH1R, and TC-MCH 7c is a phenylpyridone derivative with MCH1R Ki of 3.4 nM against human. In mice, MCH1R Ki was 3.0 nM.