G Protein-Coupled Receptor Ligands

TG 100572 Hydrochloride View larger

TG 100572 Hydrochloride

AT13156L

CAS 867331-64-4

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$339.00

$339.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $152.55 Total: $15,255.00
150 $176.28 Total: $8,814.00
125 $206.79 Total: $5,169.75
110 $244.08 Total: $2,440.80
15 $288.15 Total: $1,440.75

Data sheet

Molecular FormulaC26H27Cl2N5O2
Molecular Weight512.43
CAS Numbers867331-64-4
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.Cc1cc(cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc12)-c1cc(O)ccc1Cl
ReferencesDoukas J, et al. Topical administration of a multi-targeted kinase inhibitor suppresses choroidal neovascularization and retinal edema. J Cell Physiol. 2008 Jul;216[1] 29-37.

More info

TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFR?, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively).