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G Protein-Coupled Receptor Ligands
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View larger TR antagonist 1
AT13435
CAS 500794-88-7
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $215.90 | Total: $1,079.50 |
| 1 | 10 | $182.88 | Total: $1,828.80 |
| 1 | 25 | $154.94 | Total: $3,873.50 |
| 1 | 50 | $132.08 | Total: $6,604.00 |
| 1 | 100 | $114.30 | Total: $11,430.00 |
Data sheet
| Molecular Formula | C25H23Br2NO4 |
| Molecular Weight | 561.26 |
| CAS Numbers | 500794-88-7 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)c1cc(Oc2c(Br)cc(CCC(O)=O)cc2Br)cc(C=Cc2ccncc2)c1O |
| References | Koehler K, et al. Thyroid receptor ligands. 6. A high affinity "direct antagonist" selective for the thyroid hormone receptor. J Med Chem. 2006 Nov 16;49[23] 6635-7. |
More info
TR antagonist 1 is a highly potent thyroid hormone receptor (TR) antagonist (IC50 of 36 and 22 nM for TR? and TR?, respectively) that can be used to study diseases caused by endocrine abnormalities.