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View larger ATC 0175 hydrochloride
AT22591
CAS 510733-97-8
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $27.45 | Total: $2,745.00 |
| 1 | 50 | $31.72 | Total: $1,586.00 |
| 1 | 25 | $37.21 | Total: $930.25 |
| 1 | 10 | $43.92 | Total: $439.20 |
| 1 | 5 | $51.85 | Total: $259.25 |
Data sheet
| Molecular Formula | C23H26ClF2N5O |
| Molecular Weight | 461.93 |
| CAS Numbers | 510733-97-8 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(C)(C)C=1C2=C(N=C(N[C@H]3CC[C@@H](NC(=O)C4=CC(F)=C(F)C=C4)CC3)N1)C=CC=C2.Cl |
| References | Semple G, et al. Pyrimidine-based antagonists of h-MCH-R1 derived from ATC0175 in vitro profiling and in vivo evaluation. Bioorg Med Chem Lett. 2009 ; 19[21] 6166-6171. |
More info
ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective. ATC 0175 hydrochloride has affinity for MCH1R, MCH2R, MCH1, 5-HT2B receptors and 5-HT1A receptors with IC50s of 13.5 nM, >10,000 nM, 13 nM, 9.66 nM and 16.9 nM, respectively. ATC 0175 hydrochloride exhibits antidepressant and anxiolytic effects in animal models. aTC 0175 can be used to study depression andor anxiety disorders.