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G Protein-Coupled Receptor Ligands
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View larger Ticolubant
AT28974
CAS 154413-61-3
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $152.15 | Total: $760.75 |
| 1 | 10 | $128.88 | Total: $1,288.80 |
| 1 | 25 | $109.19 | Total: $2,729.75 |
| 1 | 50 | $93.08 | Total: $4,654.00 |
| 1 | 100 | $80.55 | Total: $8,055.00 |
Data sheet
| Molecular Formula | C23H19Cl2NO3S |
| Molecular Weight | 460.37 |
| CAS Numbers | 154413-61-3 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(=CC(O)=O)C1=C(OCCC2=CC=CC=C2)C=CC(CSC3=C(Cl)C=CC=C3Cl)=N1 |
| References | Gearing KL, et al. Complex chimeras to map ligand binding sites of GPCRs. Protein Eng. 2003;16[5] 365-372. |
More info
Ticolubant is orally active leukotriene B4 antagonist with high affinity for the human neutrophil LTB4 receptor (Ki = 0.78 nM), blocks LTB4-induced Ca2+ migration with an IC50 of 6.6