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View larger BMS-986278
AT39647
CAS 2170126-74-4
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $167.45 | Total: $837.25 |
| 1 | 10 | $141.84 | Total: $1,418.40 |
| 1 | 25 | $120.17 | Total: $3,004.25 |
| 1 | 50 | $102.44 | Total: $5,122.00 |
| 1 | 100 | $88.65 | Total: $8,865.00 |
Data sheet
| Molecular Formula | C22H31N5O5 |
| Molecular Weight | 445.51 |
| CAS Numbers | 2170126-74-4 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCCN(C)C(=O)OCc1c(nnn1C)-c1ccc(O[C@H]2CCC[C@@H](C2)C(O)=O)c(C)n1 |
| References | Cheng PTW, et al. Murphy BJ. Discovery of an Oxycyclohexyl Acid Lysophosphatidic Acid Receptor 1 [LPA1] Antagonist BMS-986278 for the Treatment of Pulmonary Fibrotic Diseases. J Med Chem. 2021 Nov 11;64[21] 15549-15581. |
More info
BMS-986278 is an orally active and potent hemophosphatidic acid receptor 1 (LPA1) antagonist with Kb values of 6.9 nM and 4.0 nM for human and mouse LPA1, respectively.BMS-986278 may be investigated for use in idiopathic pulmonary fibrosis.