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View larger BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride
AT40111L
CAS 2691796-83-3
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $85.05 | Total: $8,505.00 |
| 1 | 50 | $98.28 | Total: $4,914.00 |
| 1 | 25 | $115.29 | Total: $2,882.25 |
| 1 | 10 | $136.08 | Total: $1,360.80 |
| 1 | 5 | $160.65 | Total: $803.25 |
Data sheet
| Molecular Formula | C41H45Cl3N4O5 |
| Molecular Weight | 780.18 |
| CAS Numbers | 2691796-83-3 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.Cl.Cc1c(COc2cc(OCc3cccc(c3)C#N)c(CN3CCCCC3C(=O)N3CCNCC3)cc2Cl)cccc1-c1ccc2OCCOc2c1 |
More info
BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride, a resorcinol di-Ph ether scaffold-based programmed cell death-1 (PD-1)programmed cell death ligand 1 (PD-L1) inhibitor, inhibits the PD-1PD-L1 interaction with an IC50 of 39.2 nM. It contains the target protein PD-1PD-L1 ligand and PROTAC linker, which can be used to synthesize PROTAC PD-1PD-L1 degrader-1 and has anticancer activity. Additionally, it serves as a diluent for the preparation of tablets for direct compression.