G Protein-Coupled Receptor Ligands

AZ876 View larger

AZ876

AT5178

CAS 898800-26-5

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$38.00

$38.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $17.10 Total: $1,710.00
150 $19.76 Total: $988.00
125 $23.18 Total: $579.50
110 $27.36 Total: $273.60
15 $32.30 Total: $161.50

Data sheet

Molecular FormulaC24H29N3O3S
Molecular Weight439.57
CAS Numbers898800-26-5
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(C)(C)N1C(=O)C(Nc2ccc(cc2)N2CCCCC2)=C(c2ccccc2)S1(=O)=O
Referencesvan der Hoorn J et al. Low dose of the liver X receptor agonist, AZ876, reduces atherosclerosis in APOE*3Leiden mice without affecting liver or plasma triglyceride levels. Br J Pharmacol. 2011 Apr;162[7] 1553-63.

More info

AZ876 is a potent, highly selective LXR agonist with KiEC50 of 76 nM and 1173 nM for hLXR? and hLXR? respectively.