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G Protein-Coupled Receptor Ligands
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View larger MRGPRX4 modulator-2
AT61183
CAS 2492595-24-9
1000 Items
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $37.40 | Total: $187.00 |
| 1 | 10 | $31.68 | Total: $316.80 |
| 1 | 25 | $26.84 | Total: $671.00 |
| 1 | 50 | $22.88 | Total: $1,144.00 |
| 1 | 100 | $19.80 | Total: $1,980.00 |
Data sheet
| Molecular Formula | C15H9ClF4O3 |
| Molecular Weight | 348.68 |
| CAS Numbers | 2492595-24-9 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C(O)C1=CC=CC(=C1F)COC2=CC=C(C=C2Cl)C(F)(F)F |
| References | Adam YEAGER, et al. Modulators of mas-related g-protein receptor x4 and related products and methods. WO2020198537A1 [compound 1-55] |
More info
MRGPRX4 modulator-2 (compound 1-55) is a highly potent antagonist of MRGPRX4 with an IC50 value of less than 100 nM. Its notable applications include research on autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson's Syndrome, and various chronic itch conditions [1].