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G Protein-Coupled Receptor Ligands
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View larger PARP12TNKS12-IN-1
AT72437
CAS 2243453-32-7
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $51.00 | Total: $255.00 |
| 1 | 10 | $43.20 | Total: $432.00 |
| 1 | 25 | $36.60 | Total: $915.00 |
| 1 | 50 | $31.20 | Total: $1,560.00 |
| 1 | 100 | $27.00 | Total: $2,700.00 |
Data sheet
| Molecular Formula | C35H31FN6O5 |
| Molecular Weight | 634.66 |
| CAS Numbers | 2243453-32-7 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COC1=CC=C(NC(C2=CC=C(NC(N3CCN(CC3)C(C4=CC(CC5=NNC(C6=C5C=CC=C6)=O)=CC=C4F)=O)=O)C=C2)=O)C=C1 |
| References | Xu Y, et al. Rational design, synthesis and biological evaluation of dual PARP-12 and TNKS12 inhibitors for cancer therapy. Eur J Med Chem. 2022 Jul 5;237 114417. |
More info
PARP12TNKS12-IN-1 is a multi-target inhibitor of PARP-1, PARP-2, TNKS1, and TNKS2, with potential anti-tumor activity that induces apoptosis.