G Protein-Coupled Receptor Ligands

PARP12TNKS12-IN-1 View larger

PARP12TNKS12-IN-1

AT72437

CAS 2243453-32-7

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$60.00

$60.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $27.00 Total: $2,700.00
150 $31.20 Total: $1,560.00
125 $36.60 Total: $915.00
110 $43.20 Total: $432.00
15 $51.00 Total: $255.00

Data sheet

Molecular FormulaC35H31FN6O5
Molecular Weight634.66
CAS Numbers2243453-32-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOC1=CC=C(NC(C2=CC=C(NC(N3CCN(CC3)C(C4=CC(CC5=NNC(C6=C5C=CC=C6)=O)=CC=C4F)=O)=O)C=C2)=O)C=C1
ReferencesXu Y, et al. Rational design, synthesis and biological evaluation of dual PARP-12 and TNKS12 inhibitors for cancer therapy. Eur J Med Chem. 2022 Jul 5;237 114417.

More info

PARP12TNKS12-IN-1 is a multi-target inhibitor of PARP-1, PARP-2, TNKS1, and TNKS2, with potential anti-tumor activity that induces apoptosis.