G Protein-Coupled Receptor Ligands

Lats-IN-1 View larger

Lats-IN-1

AT9053

CAS 1424635-83-5

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$57.00

$57.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $25.65 Total: $2,565.00
150 $29.64 Total: $1,482.00
125 $34.77 Total: $869.25
110 $41.04 Total: $410.40
15 $48.45 Total: $242.25

Data sheet

Molecular FormulaC18H14N4OS
Molecular Weight334.39
CAS Numbers1424635-83-5
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C(N=c1sccn1Cc1ccccc1)c1c[nH]c2ncccc12
ReferencesNathaniel Kastan, et al. Small-molecule inhibition of Lats kinases promotes Yap-dependent proliferation in postmitotic mammalian tissues. bioRxiv 2020.02.11.944157.

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Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues.