G Protein-Coupled Receptor Ligands

Cortistatin-14 View larger

Cortistatin-14

ATP1570

CAS 186901-48-4

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$83.00

$83.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $37.35 Total: $3,735.00
150 $43.16 Total: $2,158.00
125 $50.63 Total: $1,265.75
110 $59.76 Total: $597.60
15 $70.55 Total: $352.75

Data sheet

Molecular FormulaC81H114N20O18S2
Molecular Weight1720.03
CAS Numbers186901-48-4
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(O)C1NC(=O)C(CCCCN)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2ccccc2)NC(=O)C(CC(N)=O)NC(=O)C(CCCCN)NC(=O)C(CSSCC(NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(Cc2ccccc2)NC1=O)C(=O)NC(CCCCN)C(O)=O)NC(=O)C1CCCN1
ReferencesDe Lecea L, et al. A cortical neuropeptide with neuronal depressant and sleep-modulating properties. Nature. 1996 May 16;381[6579] 242-5.

More info

Cortistatin-14, a neuropeptide structurally similar to growth inhibitor-14, has anticonvulsant and neuroprotective effects and impairs recognition memory consolidation in mice through activation of sst(2), growth hormone-releasing peptide, and GABA(AB) receptor, which can be used to study sepsis-induced cognitive impairment.