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Adaphostin
AOB6827
CAS: 241127-58-2
Chemical Name: NSC-680410; 1-Adamantyl 4-((2,5-dihydroxybenzyl)amino)benzoate
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity (mg or Unit) | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|
| 100 | $4.95 | Total: $495.00 |
| 50 | $5.72 | Total: $286.00 |
| 25 | $6.71 | Total: $167.75 |
| 10 | $7.92 | Total: $79.20 |
| 5 | $9.35 | Total: $46.75 |
Data sheet
| Molecular Formula | C24H27NO4 |
| Molecular Weight | 393.48 |
| CAS Numbers | 241127-58-2 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 4-[[(2,5-Dihydroxyphenyl)methyl]amino]benzoic acid tricyclo[3.3.1.13,7]dec-1-yl ester |
| InChl Key | YJZSUCFGHXQWDM-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C24H27NO4/c26-21-5-6-22(27)19(10-21)14-25-20-3-1-18(2-4-20)23(28)29-24-11-15-7-16(12-24)9-17(8-15)13-24/h1-6,10,15-17,25-27H,7-9,11-14H2 |
| SMILES Code | O=C(C4=CC=C(NCC5=C(O)C=CC(O)=C5)C=C4)OC12CC(C3)CC(CC3C2)C1 |
| References | 1) Svingen et al (2000) Effects of the bcl/abl kinase inhibitors AG957 and NSC 680410 on chronic myelogenous leukemia cells in vitro. Clin.Cancer Res. 6 237 PMID: 10656455 2) Avramis et al (2002) In vitro and in vivo evaluations of the tyrosine kinase inhibitor NSC 680410 against human leukemia and glioblastoma cell lines. Cancer Chemother.Pharmacol. 50 479 PMID: 12451475 3) Mow et al (2002) Effects of bcr/abl kinase inhibitors STI571 and adaphostin (NSC 680410) on chronic myelogenous leukemia cells in vitro. Blood 99 664 PMID: 11781252 |
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