GABA Receptors

Phaclofen View larger

Phaclofen

AT23147

CAS 114012-12-3

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$183.00

$183.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $82.35 Total: $8,235.00
150 $95.16 Total: $4,758.00
125 $111.63 Total: $2,790.75
110 $131.76 Total: $1,317.60
15 $155.55 Total: $777.75

Data sheet

Molecular FormulaC9H13ClNO3P
Molecular Weight249.63
CAS Numbers114012-12-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=P(O)(O)CC(C1=CC=C(Cl)C=C1)CN
ReferencesJohnson CM, et al. The antitussive cloperastine improves breathing abnormalities in a Rett Syndrome mouse model by blocking presynaptic GIRK channels and enhancing GABA release. Neuropharmacology. 2020;176 108214.

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Phaclofen (3-Amino-2-(4-chlorophenyl)propanephosphonic acid) is a selective GABAB receptor antagonist, which can partially antagonize the sedative effect of (-)-baclofen, and reversibly antagonize the inhibition of cholinergic convulsive response of guinea pig ileum and distal colon by baclofen or GABA. Inhibits the cholinergic convulsive response in the guinea pig ileum and distal colon by baclofen or GABA.