GABA Receptors

COR659 View larger

COR659

AT36520

CAS 544450-68-2

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$69.00

$69.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $31.05 Total: $3,105.00
150 $35.88 Total: $1,794.00
125 $42.09 Total: $1,052.25
110 $49.68 Total: $496.80
15 $58.65 Total: $293.25

Data sheet

Molecular FormulaC16H16ClNO3S
Molecular Weight337.82
CAS Numbers544450-68-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCCc1c(C)sc(NC(=O)c2ccc(Cl)cc2)c1C(=O)OC
ReferencesFrancesca Ferlenghi, et al. The GABA B receptor positive allosteric modulator COR659 In vitro metabolism, in vivo pharmacokinetics in rats, synthesis and pharmacological characterization of metabolically protected derivatives. Eur J Pharm Sci. 2020 Dec 1;155 105544.

More info

COR659 is a 2-acylaminothiophene derivative able to suppress alcohol and chocolate self-administration in rats, likely via positive allosteric modulation of the GABAB receptor and antagonisminverse agonism at the cannabinoid CB1 receptor.