Glucocorticoid Receptor

GW-870086 View larger

GW-870086

AT15451

CAS 827319-43-7

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$31.00

$31.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $13.95 Total: $1,395.00
150 $16.12 Total: $806.00
125 $18.91 Total: $472.75
110 $22.32 Total: $223.20
15 $26.35 Total: $131.75

Data sheet

Molecular FormulaC31H39F2NO6
Molecular Weight559.64
CAS Numbers827319-43-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES Code[H][C@@]12C[C@@H](C)[C@](OC(=O)C3C(C)(C)C3(C)C)(C(=O)OCC#N)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C
ReferencesUings IJ, et al. Discovery of GW870086 a potent anti-inflammatory steroid with a unique pharmacological profile. Br J Pharmacol. 2013 Jul;169[6] 1389-403.

More info

GW-870086 is an effective anti-inflammatory agent. GW-870086 also plays a role in a glucocorticoid receptor agonist (pIC50: 10.1 in A549 cells expressing NF-?B).