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View larger PD90780
AOB4201
CAS: 77422-99-2
Chemical Name: PD-90780; 7-(Benzoylamino)-4,9-dihydro-4-methyl-9-oxopyrazolo[5,1-b]quinazoline-2-carboxylic acid
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $17.85 | Total: $89.25 |
| 1 | 10 | $15.12 | Total: $151.20 |
| 1 | 25 | $12.81 | Total: $320.25 |
| 1 | 50 | $10.92 | Total: $546.00 |
| 1 | 100 | $9.45 | Total: $945.00 |
Data sheet
| Molecular Formula | C19H14N4O4 |
| Molecular Weight | 362.34 |
| CAS Numbers | 77422-99-2 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 7-(Benzoylamino)-4,9-dihydro-4-methyl-9-oxo-pyrazolo[5,1-b]quinazoline-2-carboxylic |
| InChl Key | IAZAGXDMMVWYKF-UHFFFAOYSA-N |
| SMILES Code | O=C(C4=CC=CC=C4)NC1=CC=C3C(C(N2C(N3C)=CC(C(O)=O)=N2)=O)=C1 |
| References | 1) Eibl Structural, biological, and pharmacological strategies for the inhibition of nerve growth factor. Neurochem.Int. 2012 PMID: 23103525 2) Longo Small molecule modulation of p75 neurotrophin receptor functions. CNS Neurol.Disord.Drug Targets 2008 PMID: 18289033 3) Colquhoun Differential activity of the nerve growth factor (NGF) antagonist PD90780 [7-(benzolylamino)-4,9-dihydro-4-methyl-9-oxo-pyrazolo[5,1-b]quinazoline-2-carboxylic acid] suggests altered NGF-p75NTR interactions in the presence of TrkA. J.Pharmacol.Exp.Ther. 2004 PMID: 15051797 |
More info
Nerve growth factor (NGF) antagonist