Growth Factors Receptors

Sunvozertinib View larger

Sunvozertinib

AT64124

CAS 2370013-12-8

More details

Molarity Calculation Cart®

HOW TO ORDER

$26.00

$26.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $11.70 Total: $1,170.00
150 $13.52 Total: $676.00
125 $15.86 Total: $396.50
110 $18.72 Total: $187.20
15 $22.10 Total: $110.50

Data sheet

Molecular FormulaC29H35ClFN7O3
Molecular Weight584.08
CAS Numbers2370013-12-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOc1cc(N2CC[C@H](C2)N(C)C)c(NC(=O)C=C)cc1Nc1nccc(Nc2cc(Cl)c(F)cc2C(C)(C)O)n1
ReferencesZhengtao LI, et al. Erbbbtk inhibitors. WO2019149164A1.

More info

Sunvozertinib (DZD9008) is a potent ErbBs and BTK inhibitor with inhibitory effects on EGFR, Her2, and mutant epidermal growth factor. It inhibits EGFR exon 20 NPH insertion, EGFR exon 20 ASV insertion, EGFR L858R and T790M mutation, and Her2 exon 20 YVMA and EGFR WT A431, with IC50 values of 20.4, 20.4, 1.1, 7.5, and 80.4 nM, respectively.