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View larger Mavelertinib
AT21322
CAS 1776112-90-3
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $44.20 | Total: $221.00 |
| 1 | 10 | $37.44 | Total: $374.40 |
| 1 | 25 | $31.72 | Total: $793.00 |
| 1 | 50 | $27.04 | Total: $1,352.00 |
| 1 | 100 | $23.40 | Total: $2,340.00 |
Data sheet
| Molecular Formula | C18H22FN9O2 |
| Molecular Weight | 415.42 |
| CAS Numbers | 1776112-90-3 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1nn(C)cc1Nc1nc(nc2n(C)cnc12)N1C[C@@H](F)[C@@H](C1)NC(=O)C=C |
| References | Planken S, et, al. Discovery of N-[[3R,4R]-4-Fluoro-1-[6-[[3-methoxy-1-methyl-1H-pyrazol-4-yl]amino]-9-methyl-9H-purin-2-yl]pyrrolidine-3-yl]acrylamide [PF-06747775] through Structure-Based Drug Design A High Affinity Irreversible Inhibitor Targeting Onc |
More info
Mavelertinib (PF-06747775) is an orally available, selective and potent EGFR tyrosine kinase (EGFR TKI) inhibitor with inhibitory effects on T790ML858R and T790MDel, and can be used in the study of oncology and respiratory diseases.