Growth Factors Receptors

PAT-505 View larger

PAT-505

AT12372

CAS 1782070-22-7

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$254.00

$254.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $114.30 Total: $11,430.00
150 $132.08 Total: $6,604.00
125 $154.94 Total: $3,873.50
110 $182.88 Total: $1,828.80
15 $215.90 Total: $1,079.50

Data sheet

Molecular FormulaC23H18ClF2N3O2S
Molecular Weight473.92
CAS Numbers1782070-22-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCCn1cc(cn1)-n1c(C2CC2)c(Sc2cccc(C(O)=O)c2F)c2ccc(Cl)c(F)c12
ReferencesBain G, et al. Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis. J Pharmacol Exp Ther. 2017 Jan;360[1] 1-13. Epub 2016 Oct 17.

More info

PAT-505 is an orally available, selective and potent inhibitor of autologous epidermal growth factor (IC50 2 nM in Hep3B cells, 9.7 nM in human blood, 62 nM in mouse plasma).