Growth Factors Receptors

JCN037 View larger

JCN037

AT8431

CAS 2305154-31-6

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$30.00

$30.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $13.50 Total: $1,350.00
150 $15.60 Total: $780.00
125 $18.30 Total: $457.50
110 $21.60 Total: $216.00
15 $25.50 Total: $127.50

Data sheet

Molecular FormulaC16H11BrFN3O2
Molecular Weight376.18
CAS Numbers2305154-31-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeFc1c(Br)cccc1Nc1ncnc2cc3OCCOc3cc12
ReferencesJonathan E. Tsang, et al. Development of a Potent Brain-Penetrant EGFR Tyrosine Kinase Inhibitor against Malignant Brain Tumors. ACS Med. Chem. Lett. 2020. May 1.

More info

JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRv? with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively).