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Histamine Receptors
- Protein Control Ligand
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View larger Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $20.25 | Total: $2,025.00 |
| 1 | 50 | $23.40 | Total: $1,170.00 |
| 1 | 25 | $27.45 | Total: $686.25 |
| 1 | 10 | $32.40 | Total: $324.00 |
| 1 | 5 | $38.25 | Total: $191.25 |
Data sheet
| Molecular Formula | C18H23N3O2 |
| Molecular Weight | 313.39 |
| CAS Numbers | 1005402-19-6 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O(CCCN1[C@H](C)CCC1)C2=CC=C(C=C2)C=3C=CC(=O)NN3 |
| References | Hudkins RL, et al. Discovery and characterization of 6-{4-[3-[R]-2-methylpyrrolidin-1-yl]propoxy]phenyl}-2H-pyridazin-3-one [CEP-26401, irdabisant] a potent, selective histamine H3 receptor inverse agonist. J Med Chem. 2011 Jul 14;54[13] 4781-92. |
More info
Irdabisant (CEP-26401) (CEP-26401) is a selective, orally active and blood-brain barrier (BBB) penetrant antagonistinverse agonist of histamine H3 receptor (H3R) (rat H3R Ki= 7.2 nM, human H3R Ki= 2.0 nM). Irdabisant exhibits relatively low inhibitory activity against hERG current (IC50= 13.8 ?M). Irdabisant exhibits cognition-enhancing and wake-promoting activities in the rat social recognition model. Irdabisant can be used for research on schizophrenia or cognitive impairment.