Histamine Receptors

Meclizine View larger

Meclizine

AT40652

CAS 569-65-3

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$166.00

$166.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $74.70 Total: $7,470.00
150 $86.32 Total: $4,316.00
125 $101.26 Total: $2,531.50
110 $119.52 Total: $1,195.20
15 $141.10 Total: $705.50

Data sheet

Molecular FormulaC25H27ClN2
Molecular Weight390.95
CAS Numbers569-65-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCc1cccc(CN2CCN(CC2)C(c2ccccc2)c2ccc(Cl)cc2)c1
ReferencesPriti N. Patel, et al. Safety and Efficacy in the Treatment and Prevention of Motion Sickness. Clinical Medicine Insights Therapeutics. 2011;3.

More info

Meclizine, also known as Meclozine, is a piperazine class H1 antagonist with antihistamine properties that inhibits the interaction of histamine at H1 receptors reversibly. It serves as an effective anti-motion sickness agent, able to cross the blood-brain barrier. Additionally, Meclizine acts as an agonist ligand for the mouse constitutive androstane receptor (CAR) and an inverse agonist for human CAR, making it useful in research on polyQ toxicity disorders, including Huntington's disease.